[Article] Key role of the expression of bone morphogenetic proteins in increasing the osteogenic activity of osteoblast-like cells exposed to shock waves and seeded on bioactive glass-ceramic scaffolds for bone tissue engineering
نویسندگان
چکیده
In this work, the role of shock-wave (SW)-induced increase of bone morphogenetic proteins (BMPs) in modulating the osteogenic properties of osteoblast-like cells seeded on a bioactive scaffold was investigated using gremlin as a BMP antagonist. Bone-like glass-ceramic scaffolds, based on a silicate experimental bioactive glass (CEL2) developed at the Politecnico di Torino, were produced by the sponge replication method and used as porous substrates for cell culture.
منابع مشابه
Shock waves induce activity of human osteoblast-like cells in bioactive scaffolds.
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